Current researches for giant cell tumor of bone and its adjuvant therapy
LIN Yulin
ZHANG Yu
Abstract：Being a kind of common locally-aggressive primary bone tumor, giant cell tumor of bone (GCTB) mostly occurs in metaphysis of long bones in adults between 20 to 40 years old, with uncertain biological behavior and relative high local recurrence rate. Major treatment included intralesional curettage and segmental resection, in which the combination of curettage and physical or chemical adjuvant therapy could enhance local control effects and thus reduce the recurrence of tumor. Based on reviews of epidemiological characteristics, tumor grading, diagnosis and surgical treatment, current researches of high speed drilling, temperature ablation (argon knife, microwave, liquid nitrogen, argon-helium knife), bone cement filling, as well as chemical adjuvant (phenol, high concentration ethanol and so on) therapy were focused in this paper, so as to provide references for adjuvant treatment selection in patients with GCTB.
Keywords：Giant cell tumors of boneEpidemiologyPathologyRadiological diagnosisCombined modality therapyCurettageDrillHyperthermiainducedArgonMicrowavesCryotherapyNitrogenHeliumBone cementsChemotherapyadjuvant
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 112-119 )