Comparison of high-viscosity and low-viscosity bone cement in percutaneous kyphoplasty

DA Xiaowei; LI Qizhong; OU Jiexiong; DU Guocong

doi:10.3969/j.issn.1674-666X.2015.02.003

Abstract：Objective To compare the curative effect of high-viscosity and low-viscosity bone cement in percutaneous kyphoplasty (PKP) for the treatment of osteoporotic vertebral compression fracture (OVCF). Methods Sixty OVCF patients treated by PKP from March 2013 to September 2014 in Gaoyao People's Hospital were randomly divided into low-viscosity group (treated by low-viscosity bone cement PKP) and high-viscosity group (treated by high-viscosity bone cement PKP), with 30 patients in each group. The height of involving vertebrae and kyphosis Cobb angle in two groups were compared before and after operation; Visual analogue scale (VAS), Oswestry disability index (ODI) and 36-item short form health survey questionnaires (SF-36) score were adopted to evaluate the pain degree, dysfunction, quality of life and other subjective sensations of the patients; Complications such as bone cement leakage and recent pulmonary embolism were also recorded. Results The injected bone cement volume in low-viscosity group and high-viscosity group were (3.1 ± 0.6) mL and (3.6 ± 0.8) mL respectively, the difference was statistically significant (P <0.05). The patients were followed up for 3-6 months (the average was 4 months). VAS score, ODI, SF-36 score, vertebral height and kyphosis Cobb angle in two groups at 1 d and 3 months after the surgery were better than preoperative ones (P<0.05). Among them, the above postoperative indicators in high-viscosity group at 1 day and 3 months after the operation were better than those in low-viscosity group (P <0.05). Bone cement leakage and recent pulmonary embolism occurred in 6, 2 cases in low-viscosity group and 1, 0 cases in high-viscosity one, showing statistical differences of complication incidences between two groups (P <0.05). Conclusion Compared with low-viscosity bone cement PKP, short-term efficacy of high-viscosity bone cement PKP in the treatment of OVCF is more ideal with lower complications of bone cement leakage and recent pulmonary embolism, which is worthy of clinical application and popularization.