Analysis of Adverse Events Following Immunization of Human Papillomavirus Vaccine in Shenzhen City,from 2017 to 2021
ZHANG Yanwei
WANG Yuanling
HUANG Fang
XIE Xu
Abstract：Objective To analyze the incidence of Adverse Events Following Immunization(AEFI)with Human Papillomavirus(HPV)vaccine and the distribution characteristics of clinical symptoms in Shenzhen City from 2017 to 2021.Methods Collecting the information of imported HPV vaccination and AEFI data from 2017 to 2021 in Shenzhen City through Shenzhen Immunization Program Information System and the China AEFI Surveillance Information Management System.Results The Overall AEFI incidence of imported HPV vaccines was 10.88 per 100 000 doses during 2017 to 2021,in Shenzhen.Incidence for HPV2,HPV4 and HPV9 were 17.01 per 100 000 doses,9.35 per 100000 doses and 11.68 per 100 000 doses,respectively.Incidence of common adverse reactions and rare adverse reactions were 6.05 per 100 000 doses and 2.84 per 100 000 doses,respectively.The incidence of serious adverse reaction report was 0.12 per 100 000 doses.Conclusion The AEFI surveillance system of HPV vaccine in Shenzhen has good sensitivity,and the reported incidence is within the expected range,and serious AEFI are rare.
Keywords：Human Papillomavirus VaccineAdverse Events Following Immunizationsurveillance
Publication Date：2023-12-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 822-825 )