Research progress on vitamin D and diabetic nephropathy
HU Zhi-yong
ZHU Jian-liang
LIU Xiao-hong
ZHANG Zeng-li
Abstract：Diabetic nephropathy is one of the common complications of diabetes.Epidemiological studies have shown that vitamin D deficiency is associated with the development of diabetic nephropathy.Therefore, Vitamin D may be an important factor affecting diabetic nephropathy.At present, the relationship between vitamin D and the pathogenesis of diabetic nephropathy and vitamin D supplementation improve the status of patients with diabetic nephropathy have become a research hotspot.This article summarized relevant research at home and abroad in recent years, and the system comprehensively introduced the research progress between vitamin D and diabetic nephropathy from these aspects which included relationship between vitamin D and diabetic nephropathy, protective mechanism of vitamin D on diabetic nephropathy and application of vitamin D in patients with diabetic nephropathy.The physiological mechanism of the relationship between vitamin D and diabetic nephropathy was introduced, and the causes of the difference in the prevention and treatment of diabetic nephropathy in the population experiment were explained from the aspects of vitamin D receptor signaling pathway and gene polymorphism.In the future, with the further revealing role of vitamin D in the pathogenesis of diabetic nephropathy, it will provide better guidance for the treatment of patients with diabetic nephropathy and the prevention of complications.
Keywords：vitamin Ddiabetic nephropathyresearch progress
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 195-200 )