Construction of a Rapid Screening Method for Multiple Pesticide Residues in Tomatoes Based on TD-ESI-MS/MS
ZHANG Qingqing
ZHAO Xinyu
FAN Yixuan
TAN Mengnan
SONG Ye
XU Min
YAN Xinhuan
LIU Xuemei
Abstract：To meet the demand for high-throughput and rapid screening of pesticide residues in large batches of tomatoes and to improve the efficiency of quality and safety supervision,this study developed a rapid qualitative screening method for pesticide residues in tomatoes based on thermal desorption-electrospray ionization-in situ tandem mass spectrometry(TD-ESI-MS/MS).By optimizing and establishing a"one-circle scraping"as the standard sampling method,a rapid detection method for 237 pesticides in tomatoes was established,enabling the analysis of a single sample within 3 minutes.Methodological validation showed good reproducibility and precision.Screening results for commercially available tomato samples were consistent with those obtained by ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS).The rapid screening method established in this study had the advantages of fast detection and accurate qualification.It was suitable for rapid preliminary screening of large batches of tomato samples,could significantly enhance the efficiency of pesticide residue detection,and provide robust technical support for tomato quality and safety supervision.
Keywords：TD-ESI-MS/MSrapid screeningtomatopesticide residues
Publication Date：2026-04-30
Online Publishing Date：2026-08-28(First online date of this platform, not the publication date of the document)
Pages：12( 13-24 )