Study on Serum Vitamin A/D Level of Overweight and Obese Children Aged 3～6 Years

Zhao Weiting; Fu Huanhuan; Dai Huimin

doi:10.3969/j.issn.1001-568X.2025.04.0012

Abstract：OBJECTIVE To study the serum vitamin A and vitamin D levels of overweight and obese children aged 3～6 years,to provide a reference basis for the prevention and treatment of overweight and obesity in clinical children.METHODS 163 cases of overweight and obese children treated in Weifang Community Health Service Center of Pudong New Area from January 2021 to October 2023 were analyzed retrospectively.According to the inclusion and exclusion criteria,90 children were finally included as a case group for study.According to the BMI values of all children,90 children were divided into overweight(n=43)group and obesity group(n=47).The levels of vitamin A and vitamin D were detected in all children,and the levels of low-density lipoprotein cholesterol(LDL-C),triglyceride(TG),total cholesterol(TC)and high-density lipoprotein cholesterol(HDL-C)were determined at the time of diagnosis.Pearson correlation was used to analyze the correlation between the levels of vitamin A and vitamin D and lipid metabolism.RESULTS Among 90 children,16 cases(17.78%)were deficient in vitamin A,32 cases(35.56%)were deficient.vitamin D deficiency was found in 21 cases(23.33%),deficiency in 34 cases(37.78%).The levels of vitaminA and vitamin D were higher than those in obese group(t=4.166,2.084,P＜0.05).The levels of LDL-C,TG,TC were lower than those of obese group,and HDL-C was higher than that of obese group(t=4.776,7.947,5.513,3.547,P＜0.05).The level of vitamin D and vitamin A in overweight and obese children aged 3～6 years was negatively correlated with LDL-C,TG and TC(r=-0.306,-0.346,-0.252,0.406,P＜0.05)and positively correlated with HDL-C(r=0.406,P＜0.01).CONCLUSION The levels of serum vitamin A and vitamin D in overweight and obese children aged 3～6 years are decreased in different degrees,and there is a significant correlation with the level of lipid metabolism.Detecting the levels of serum vitamin A and vitamin D in children is helpful to prevent the occurrence of overweight and obesity in preschool.