Pathogen Surveillance of Viral Diarrhea under 5 Years Old Children in Pingliang from 2022 to 2023

Tian Xianghong; He Junxia; Hu Yu; Yan Wenhui; Liang Danfeng

doi:10.3969/j.issn.1001-568X.2024.09.0017

Abstract：OBJECTIVE To understand the pathogenic composition and epidemic characteristics of viral diarrhea in Pingliang,and to provide reference for scientific and effective prevention and control of viral diarrhea epidemic and clinical treatment.METHODS Stool samples of hospitalized children under 5 years old with diarrhea were collected from sentinel hospitals in Pingliang from 2022 to 2023,and virology detection was performed by real-time fluorescent PCR method,and the experimental results were statistically analyzed.RESULTS In 214 samples the total positive detection rate was 49.07%syn-position followed by group A Rotavirus(26.17%),Norovirus(20.09%),Intestinal Adenovirus(6.07%),Zaruvirus(5.61%)and Astrovirus(4.21%).The dominant strains of group A Rotavirus and Norovirus were G9P[8]and GII(83.93%and 95.35%).There was statistically significant difference in the positive rate of the virus between different age groups(χ2=69.134,P＜0.05).The positive rate of the virus in 13 to 24 months age group was the highest(87.50%),and that in 0 to 6 months age group was the lowest(18.92%).There was no statistically significant difference in virus detection rates between different genders(P＞0.05).CONCLUION Infants under 2 years old were high incidence group of viral diarrhea infection in children aged 0～5 years old in Pingliang,the high incidence age of group A Rotavirus and Norovirus was 13～24 months old.The group A Rotavirus had a high incidence in the first quarter,while Norovirus had a high incidence in the third quarter.In the future,it should continue to strengthen the surveillance of viral diarrhea,and carry out targeted prevention and control measures to provide a basis for scientific prevention and control of viral diarrhea.