Comparison and Insight of Domestic and Foreign Thalassemia Prevention Policies

Luo Bingxing; Weng Junling; Qiao Jingyi; Yuan Jiaqi; Yan Juntao; Ming Jian; Wei Yan; Chen Yingyao

doi:10.3969/j.issn.1001-568X.2023.12.0007

Abstract：OBJECTIVE To review the typical countries with outstanding progress in the policies on thalassemia prevention and the prevention of thalassemia in China,summarize the practical experience in the prevention of thalassemia in typical countries,and provide policy reference for the prevention of thalassemia in China.METHODS The literature of thalassemia prevention in Cyprus,Italy,Thailand and Malaysia was searched in PubMed,EMBASE,Web of Science databases.Thalassemia policy documents since 2009 were retrieved from official government websites such as the official website of National Health Commission of the People's Re-public of China.RESULTS Typical countries build a thalassemia prevention network in terms of intensive education on thalassemia knowledge,genetic screening,prenatal diagnosis and genetic counseling,and provision of standardized treatment modalities.China has basically formed a thalassemia prevention model led by the government,implemented by hospitals and supplemented by social or-ganizations.CONCLUSION China should continue to improve the thalassemia prevention program,carry out family-based population screening for thalassemia,strengthen the construction of clinical diagnosis and treatment capacity for thalassemia,establish a nation-al thalassemia registry,and strengthen international cooperation on thalassemia to develop the"the Belt and Road"strategy.