Mesonephric-like carcinosarcoma of the ovary:report of a case
HAO Yingying
JIANG Lei
LIU Jing
Abstract：This article reports a rare case of ovarian mesonephric-like carcinosarcoma. The patient underwent total hysterectomy with bilateral salpingo-oophorectomy due to a pelvic mass found during a physical examination. Pathological examination showed a cystic-solid tumor. Microscopically, the features were distinct: approximately 60% was mesonephric-like adenocarcinoma (with glandular/ papillary structures, expressing CK/TTF1/PAX8), and approximately 40% was high-grade sarcoma with rhabdomyosarcomatous differentiation (expressing Desmin/Myogenin). Immunohistochemistry clearly distinguished the carcinoma and sarcoma components. This case had a poor prognosis and provided detailed clinical pathological data for this extremely rare gynecological malignancy. Follow-up until June 1, 2025, showed recurrence and metastasis.
Keywords：MLAMesonephric-like carcinosarcomaOvaryClinical pathologyDiagnosis
Publication Date：2025-11-28
Online Publishing Date：2025-12-04(First online date of this platform, not the publication date of the document)
Pages：3( 1518-1520 )