Diffuse Pulmonary Meningotheliomatosis:1 case report and literature review
DENG Juan
PENG Jianlun
WANG Yan
Abstract：Objective To explore the clinical and pathological characteristics of diffuse pulmonary meningothelial tumor disease. Methods The clinical pathological features and immunophenotype of a case of diffuse pulmonary meningothelial tumor disease were analyzed retrospectively. Protein expression was detected by immunohistochemistry EnVision, and related literature was reviewed. Results A 55-year-old female patient was reported. Under the microscope, multiple nodular areas were observed. Under high magnification, tumor cells formed nests and grew along the alveolar walls and interlobular septa. The tumor cells had a mild morphology, with epithelioid, round, and oval shapes. The cytoplasm was abundant and eosinophilic. Immunophenotype: Vimentin, PR, EMA, SSTR2 were positive; CGA, SYN, TTF-1, SMA, HMB45 were negative. Conclusion Diffuse pulmonary meningothelial tumor disease is a rare lung tumor. Whether its biological behavior is benign or an indolent progressive tumor needs further study. Therefore, it is necessary to enhance the understanding and detection of diffuse pulmonary meningothelial tumor disease.
Keywords：Microscopic pulmonary meningothelial nodulesDiffuse pulmonary meningothelial tumor diseaseMultiple pulmonary nodules
Publication Date：2025-11-28
Online Publishing Date：2025-12-04(First online date of this platform, not the publication date of the document)
Pages：4( 1482-1485 )