Systemic lupus erythematosus complicated with genital herpes:report of a case and review of literature
TANG Xiaofang
SHI Haipeng
LI Fen
Abstract：Objective: To explore the clinical and pathological characteristics of systemic lupus erythematosus combined with genital herpes. Methods: A retrospective analysis was conducted on the clinical data and cytological features of a patient diagnosed with systemic lupus erythematosus combined with genital herpes at Chengdu Second People's Hospital, combined with a review of literature on the clinical and pathological characteristics of systemic lupus erythematosus combined with genital herpes. Results: The patient was a 23-year-old female with a history of systemic lupus erythematosus. She presented with vulvitis. Laboratory tests showed negative results for HSV-1-IgG, HSV-1-IgM, HSV-2-IgG, and HSV-2-IgM, as well as HSV-2 DNA. Cervical liquid-based cytology revealed multinucleated squamous epithelial cells with abundant cytoplasm, transparent, and nuclei that were crowded, interlaced, and had a 'glassy' appearance. Conclusion: Cases of systemic lupus erythematosus combined with genital herpes have typical clinical manifestations, specific and diverse cytological changes. Although the etiological examination was negative, genital herpes can still be diagnosed.
Keywords：Systemic Lupus ErythematosusGenital HerpesHerpes Simplex VirusCytopathology
Publication Date：2025-10-28
Online Publishing Date：2025-11-06(First online date of this platform, not the publication date of the document)
Pages：3( 1361-1363 )