Appendiceal mucinous adenocarcinoma with a huge pelvic abdominal mass as the initial symptom:report of a case
WANG Shengguo
Abstract：Objective: To explore the clinical pathological features, immunohistochemical expression, diagnosis, differential diagnosis, treatment, and prognosis of appendiceal goblet cell adenocarcinoma presenting as a primary clinical manifestation of a huge pelvic and abdominal tumor. Methods: A retrospective analysis of one case of appendiceal goblet cell adenocarcinoma presenting as a huge pelvic and abdominal tumor was conducted, combined with literature analysis to investigate its clinical pathological features, imaging findings, histological morphology, and immunohistochemical expression. Results: Appendiceal goblet cell adenocarcinoma with widespread metastases to both ovaries, fallopian tubes, and greater omentum. Immunohistochemical results: CK7(-), CK20(+), CDX-2(+), Vimentin(+), CEA(+), CD56, Syn, CgA (partially +), AB-PAS(+). Conclusion: Appendiceal goblet cell adenocarcinoma is rare, has strong concealment, often presents as a primary ovarian metastatic tumor, and immunohistochemical markers are helpful for diagnosis and differential diagnosis.
Keywords：Goblet cell adenocarcinomaOvarian tumorImmunohistochemistryClinical pathological characteristicsDifferential diagnosis
Publication Date：2025-08-28
Online Publishing Date：2025-09-18(First online date of this platform, not the publication date of the document)
Pages：3( 1063-1065 )