Clinical and pathological features of corded and hyalinized endometrioid carcinoma
TANG Dan
FU Ping
ZHAO Lian-hua
Abstract：Objective To investigate the clinicopathological characteristics,diagnosis,differential diagnosis,treatment,and prognosis of corded and hyalinized endometrioid carcinomas(CHEC).Methods The clinical data and pathological features of one CHEC patient were analyzed with review of relevant literatures.Results A 33 year old female with pathological diagnosis of CHEC was diagnosed.The tumor was composed of a mixture of classic low-grade endometrioid carcinoma and about 10%of sex cord-like structures and hyalinization accompanied by ossification.The FIGO staging of endometrial cancer in the 2023 version was stage IB;The patient was currently undergoing radiotherapy one month after surgery and was in good condition.Conclusion CHEC is a rare morphological variation of endometrioid carcinoma,with a younger onset age.Due to its biphasic histology,it is prone to misdiagnosis as carcinosarcoma,and accurate diagnosis depends on the pathologist's understanding of the lesion.Generally,total hysterectomy,bilateral adnexectomy,and regional lymph node dissection are performed,supplemented by postoperative radiotherapy and chemotherapy.Most patients have earlier FIGO staging and a better prognosis.
Keywords：Endometrioid carcinomasSex cord-like formationsHyalinizationClinicopathological characteristics
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1068-1071 )