Expression of CD16 and b-FGF in meningeoma and their clinicopathologic significances
WANG Qiong
ZHANG Jin-sheng
WANG Wei-bo
REN Yong
Abstract：Objective To investigate the expression of CD 16 and b-FGF in meningeoma and make a definite diagnosis.Methods The clinical presentation,histopathological feautures and immunophenoetype were analyzed in 110 cases of meningeoma.Results CD 16 was positive in most meningeoma(91.8％),while 97.0％positive cases showed both nuclear and cytoplasm staining.98.2％cases of meningeoma showed strong staining of b-FGF,while 86.1％positive cases showed both nuclear and cytoplasm staining.b-FGF protein expression was significantly higher in meningeoma than CD16.Spearman's correlation revealed that b-FGF protein expression was not correlated with CD 16.There was no significant differences between CD 16 and b-FGF in histological subtype and tumor stage.CD 16 was negative in epilepsy,adult-type diffuse gliomas,solitary fibrous tumor,liomyoma and benign fibrous histiocytoma.b-FGF was positive in epilepsy,adult-type diffuse gliomas,solitary fibrous tumor,liomyoma.And was negtive in benign fibrous histiocytoma.Conclusion CD16 and b-FGF are positive in meningeoma,and CD16 may be helpful in diagnosis of meningeoma.
Keywords：CD16b-FGFMeningeoma
Publication Date：2023-09-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 840-842,847 )