Small intestinal lipoma: a clinicopathologic analysis of 14 cases

ZHU Ran; LUO Yu-feng; WU Huan-wen; JIANG Ying

doi:10.3969/j.issn.1007-8096.2018.06.003

Abstract：Objective To study the clinicopathologic feature, diagnostic strategy and prognostic significance of small intestinal lipoma. Methods All patients previously diagnosed as small intestinal lipoma during the period from 2010 to2016 were evaluated about clinical data and histopathology, the patients were followed up and the relevant literatures were reviewed. Results In this series, there were 14 cases of small intestinal lipoma and the mean age was 51 years with a male/female ratio of 1: 1.33. The ileum was involved initially in 9 patients, the duodenum in 4 and the jejunum in 1. The major axis of the tumor ranged from 0.5-7.5 cm. It presented with intussusception when the major axis of the tumor was5 cm. Twelve cases were diagnosed as solitary nodule, and 2 cases were multiple nodules. Microscopically, nine cases were diagnosed as pure intestinal lipoma, 2 cases were intestinal lipoma with massive inflammatory cells infiltration, 1 case was multiple small intestinal lipoma with adenomatous hyperplasia of intestinal mucosa, 1 ease was single small intestinal lipoma with hamartoma hyperplasia of intestinal mucosa and 1 case was angiolipoma. Follow-up of 11-92 months showed that 13 patients were alive and 1 patient died because of postoperative vecurrence of colon cancex. Conclusion Small intestinal lipoma is very rare and has a good prognosis. The clinical manifestation are related to the size of the tumor and anatomic locations of small intestinal lipoma. The long-term stimulation of small intestinal lipoma might cause the local adenomatous and hamartoma hyperplasia of the intestinal mucosa.