Primary ependymoma of the mediastinum: a clinicopathological study
YE Wei-biao
XU Yong-qiang
LIANG Yuan-qiu
HE Jian-fang
YANG Xiang-ling
Abstract：Objective To investigate the clinicopathological characteristics,diagnosis and differential diagnosis of primary mediastinal ependymoma (PME).Methods We reported a case of PME in a 35-year-old woman.The histomorphologic,immunohistochemical and ultrastructural features of this tumor were summarized.Related literature were reviewed.Results A relatively well-circumscribed gray-yellow mass measuring 6 cm × 5 cm × 3 cm was located in the posterior mediastinum.Microscopically,the tumor was composed of cuboidal or columnar cells arranged predominately in a papillary or pseudopapillary architecture.Other growth patterns included cystic,trabecular and cribriform.The tumor cells were immunohistochemically positive for vimentin,GFAP,CD56,ER and PR.Conclusion PME is a very rare tumor with only few cases reported in the literature.Its clinical misdiagnosis is due mainly to the limited awareness of this disease.Recognizing its histomorphologic,immunohistochemical,and ultrastractural features might facilitate its diagnosis and differential diagnosis.
Keywords：EpendymomaMediastinal neoplasmHistopathologyImmunohistochemistry
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 354-357 )