Primary pulmonary Hodgkin lymphoma: a clinicopathological study
ZHANG Fang
LIN Wen-sheng
LI Teng
ZHENG Ji-chun
REN Li
Abstract：Objective To discuss and summarize the clinical pathological characteristics of primary pulmonary Hodgkin Lymphoma.Methods A case of primary pulmonary Hodgkin Lymphoma was carefully studied by histopathologic and immunohistochemistry,with general review of literatures.Results Tumor from superior lobe of right lung of a 28-year-old woman was analyzed.Histological examination showed large atypical hyperplastic lymphoid cells scattered in background of inflammation.Occasionally,atypical R-S cells were observed.Immunohistochemical staining showed that tumor cells were positive for CD30,moderate staining of PAX-5,and partially positive for CD20;The tumor was negative for LCA,CD56,ALK,S-100,HMB-45.EBER in situ hybridization was negative in this case.Conclusion Primary pulmonary Hodgkin Lymphoma is a rare malignant tumor.It is hard to diagnose due to its nonspecific clinical symptoms,and easy to confuse with other lung diseases both in histological and radiological results.It should be distinguished from diffuse large B cell lymphoma,anaplastic large cell lymphoma,large cell carcinoma,Langerhan's cell histiocytosis,and malignant melanoma.
Keywords：Hodgkin LymphomaPathological characteristicsPulmonary Lymphoma
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 576-580 )