Epithelioid hemangioendothelioma involving soft parts of the lumbar vertebra : a clinicopathological analysis
YU Lin
YUAN JIng
LI Wen-si
Abstract：Objective To investigate the clinicopathological features and differential diagnosis of epithelioid hemangioendothelioma (EHE).Methods We observed one case of EHE involving soft parts of the lumbar vertebra,using histopathological and immunohistochemical staining,with review of the related literatures.Results A 29-year-old woman presented with lumbodynia and radiating pain in the lower extremities without reason.Magnetic resonance imaging (MRI) revealed of lumbar paravertebra 4 and 5 and retroperitonal abnormal signal intensity masses,involving the vertebra and the surrounding tissues.So the tumor and the vertebra were resected.Histopathological features of the tumor cells were epithelioid,with eosinophilic cytoplasm and cytoplasmic vacuoles which occasionally contained red blood cells.Immunohistochemical staining showed the tumor cells positive for vimentin,CD31,laminin,and negative for CD34,CD68,FⅧRAg,CK,S-100,SMA,Syn and CD56;Ki-67 labeling index was 10％ . No tumor recurrence or metastasis was found by the following-up for one year and four months.Conclusions EHE is a rare vascular tumor,easily misdiagnosed as metastatic carcinoma or myoepithelial tumor.A proper diagnosis would be established according to its unique histopathological characteristics and immunohistochemical staining.
Keywords：Epithelioid hemangioendotheliomaHistopathologyImmunohistochemistryDifferential diagnosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 507-509 )