Comparison of the pathological changes of intraepithelial neoplasia and early gastric carcinoma before and after endoscopic submucosal dissection
LI Jun-hong
XIAO Hong-li
WANG Yang-kun
Abstract：Objective To investigate the reason and the difference of preoperative and postoperative pathological diagnosis by observing the pathological changes in intraepithelial neoplasia and early carcinoma by endoscopic submucosal dissection (ESD).Methods According to WHO classification and Vienna classification of esophageal gastrointestinal epithelial tumor,preoperative and postoperative pathological examination and diagnosis were compared in 62 cases of esophageal endoscopic submucosal dissection.Results The pathological diagnosis consistency rate of preoperative and postoperative was 69.4％ (43/62),the rate of low-grade intraepithelial neoplasia (category 3),high-grade intraepithelial neoplasia (category 4) and invasive carcinoma were 73.5％ (25/34),58.3％ (14/24) and 100％ (4/4),respectively.High-grade intraepithelial neoplasia increased by 41％ after operation.Conclusion The diagnosis of esophageal and gastric mucosa biopsy and pathological diagnosis after ESD are relatively lower;preoperative pathological diagnosis cannot completely represent the nature of esophageal gastric mucosal lesions.Treatment should not be limited to regular endoscopic follow-up or biopsy of pathological information.The treatment of ESD should be carried out actively.
Keywords：Gastric neoplasmaIntraepithelial neoplasiaEarly carcinomaEndoscopic submucosal dissectionPathology
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 334-337,341 )