Thyroid fonicular carcinoma-like tumor of kindney: a case report and literature review
SUN Yang-yang
CAI Lei-ming
CHENG Yu-qing
ZHOU Xiao-li
Abstract：Objective To investigate the clinicopathological features,immunophenotype and differential diagnosis of thyroid-like follocular carcinoma of the kidney (TLFCK).Methods A case of TLFCK was analyzed with conventional histopathological and immunohistochemical stains,and the relative literatures were reviewed.Results The tumor showed a well-demarcated mass in gross appearance that measured 3 cm in greatest diameter.Microscopically,the tumor had a thin fibrous capsule and was composed of a predominant thyroid-like follicular pattern (90％) with solid areas.Immunohistochemical staining showed tumor cells were diffusely positive for CKpan,CK19,PAX-2,sparsely posivitve for vimentin,but negative for TG,TTF-1,WT-1,CD10,CgA,CD56 and villin.No tumor recurrence or metastasis were observed after 18 months of postsurgery follow-up.Conclusions TLFCK is a rare subtype of renal cell carcinoma.The diagnosis of TLFCK mainly relies on histopathological and immunohistochemical finding.Differential diagnosis includes metastastic thyroid cancer,neuroendocrine carcinoma,malignant teratomas and epithelial patterns nephroblastoma.
Keywords：Kidney tumorThyroid-like follocular carcinoma of the kidneyImmunophenotypeDifferential diagnosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 190-193 )