Angiofibroma of soft tissue : clinicopathologic features and literature review
ZHANG Wei
LI Hai
SONG Guo-xin
FAN Qin-he
ZHANG Zhi-hong
LOU Jian-juan
ZHU Yan
Abstract：Purpose To investigate the clinicopathological characteristics and differential diagnosis of AFST.Methods One case of AFST was analyzed by light microscopy and immunohistochemical staining,the related literature were reviewed.Results The patient was 31-year-old female.Ultrasonography revealed a 5.5cm well-circumscribed mass in muscle with cystic change.Microscopically,the bland short-spindle or ovoid tumor cells were distributed haphazardly with abundantly branching small vessels.The stroma were variably collagenous to myxoid.Immunohistochemical stainings with Vim,EMA,ER,CD68,CD163 were positive,whereas S100,GFAP,NF,Catenin-β,SMA,CD34,ERG,LCA confirmed the absence of reactivity.Ki67 was only scattered positive nuclei (＜ 3％).There were no recurrence and metastasis after 12 month's follow-up.Conclusions AFST is a rare and benign fibrovascular soft tissue tumor;it can be distinguished from low-grade sarcoma by evaluation of histopathologic characteristics and the assistance of immunohistochemistry.
Keywords：Angiofibroma of Soft tissueImmunohistochemistryClinicopathology
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 186-189 )