Effects of simulated ship shock on the central nervous system in beagles
LI Yanteng
CHENG Gang
LIU Jiayu
XIE Shengqiang
HE Renke
HAO Fangbin
ZHANG Jianning
Abstract：Objective To investigate the effects of simulated ship shock with different intensities and postures on the central nervous system by simuating the shock environment of naval vessels through animal experiments,providing evidence for the prevention and treatment of ship shock injuries.Methods Twenty-one healthy adult male Beagle dogs were randomly assigned according to impact intensity into mild,moderate,severe impact groups and a control group.Each impact group was further divided into standing and sitting subgroups(n=3).A medium-scale shock machine was used to establish a simulated ship shock model.Vital signs were monitored immediately after impact,and neurological function scores were assessed.For sitting dogs in the severe impact group,cranial MRI(including T1WI,T2WI,and diffusion tensor imaging)and whole-spine CT were performed within 3 h after impact.Brain tissues were harvested 24 h post-impact,and pathological observation using HE staining was conducted on the parietal cortex and hippocampal regions.Results Compared with the control group,all impact groups showed significantly increased heart rate,respiratory rate,and blood pressure after impact,indicating a clear stress response,while oxygen saturation showed no significant difference.Neurological function scores of all impact groups remained within the normal range.Imaging examinations revealed no obvious traumatic changes in brain morphology,signal intensity,white matter fiber tract continuity,or spinal bony structures,even in the severe-impact sitting dogs.Pathological examination showed normal gross brain morphology,with neatly arranged and well-structured neurons in the parietal cortex and hippocampus,and no pathological changes such as edema,necrosis,hemorrhage,or inflammatory cell infiltration.Conclusion Under the impact parameters set in this experiment,although a significant physiological stress response was induced,no acute structural damage to the central nervous system or neurological deficits were observed in Beagle dogs at either macroscopic or microscopic levels.The results suggest that the central nervous system of Beagle dogs has a relatively high tolerance threshold to vertical impact loading,and their biomechanical responses may exhibit species-specific characteristics.Future studies should focus on more sensitive subclinical injury markers,long-term effects,and multi-directional composite shock environments to more comprehensively assess the potential risks of ship shock on the central nervous system.
Keywords：ship shock motionship shock injuryunderwater explosionbeaglecentral nervous systembrain injuriesspinal injuriesneurological function
Publication Date：2026-02-28
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)
Pages：6( 179-184 )