Precise identification and rapid diagnosis:key challenges and countermeasures for seawater immersion combat-related traumatic brain injury with intracranial infection
SU Shichao
HAO Fangbin
LIU Jiayu
WANG Yuxin
XIE Shengqiang
LI Wenxuan
YANG Zhijie
XU Ao
LÜ Wenying
CHENG Gang
ZHANG Jianning
Abstract：Combat-related traumatic brain injury is the leading cause of disability and mortality in modern warfare.Seawater immersion traumatic brain injury(sTBI),as a special type of composite injury,results from the combined effects of mechanical brain trauma and the physicochemical and biological impacts of seawater immersion.Seawater,rich in minerals and diverse microorganisms,can exert persistent adverse effects on wounds,hindering the normal tissue repair process.Among these factors,pathogenic microorganisms in seawater(such as Vibrio vulnificus)are prone to causing secondary infections,which not only delay wound healing and exacerbate inflammatory responses but also significantly increase the complexity of clinical treatment.Therefore,accurate identification and effective management of microbial infections associated with sTBI have become crucial for improving diagnostic and therapeutic outcomes.Currently,systematically reviewing and thoroughly investigating the common pathogenic microorganisms and diagnostic techniques for intracranial infections following sTBI is of great clinical significance for enhancing the management and survival rates of such combat-related injuries.
Keywords：traumatic brain injuryinfectionsseawaterbiomarkersVibrio infectionsdiagnostic techniques and proceduresdrug resistancebacterialwounds and injuries
Publication Date：2026-02-28
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)
Pages：6( 164-169 )