Research progress on the role of oxidative stress in acute lung injury caused by various factors
LIU Mengmeng
KONG Deqin
CHEN Ying
LIU Rui
LIU Jiangzheng
HAI Chunxu
ZHANG Xiaodi
Abstract：Acute lung injury(ALI)is a clinical syndrome of inflammation and increased permeability of pulmonary capillaries,which can lead to acute respiratory distress syndrome in severe cases.Oxidative stress is caused by the imbalance between reactive oxygen species/reactive nitrogen species generated in the body and antioxidant defense mechanism,resulting in damages of biological macromolecules such as nucleic acids,lipids,and proteins in tissue cells.This paper summarizes the relevant literature at home and abroad in recent years,and reviews the research progress of oxidative stress in ALI caused by different factors,aiming to provide reference for the treatment of ALI.
Keywords：acute lung injuryoxidative stressinfectious factorsnon-infectious factors
Publication Date：2025-11-30
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)
Pages：4( 1569-1572 )