Preparation of a close-range firearm injury model in medium-sized animals with 5.8 mm pistol and installation of vacuum sealing drainage system
HUANG Xiaoyong
NI Qianwei
WEI Ting
XU Qin
LI Jiajia
DING Yu
TAN Kai
SUN Ruizhe
GAO Zhan
Abstract：Objective To investigate the conditions and methods for the preparation of close-range firearm injury model of hind limbs in medium-sized animals with 5.8 mm pistol and the installation of vacuum sealing drainage(VSD)system.Methods Three female healthy pigs,weighing 30-35 kg and aged 3-4 months,were selected and raised in a single pen,with the temperature maintained between 20 ℃ and 25 ℃ and the humidity between 40％and 60％.The experimental animals were fed with the original feed for 3 d in the rearing room to adapt to the environment,and water was fasted 1 d before the experiment.On the day of the experiment,the experimental animals were anaesthetized and then fixed in a shooting position.After pistol shooting by a fixed soldier,the pigs were carried away from the experimental site using a stretcher,and emergency wound treatment was carried out in a safe flat area,including hemostasis,wound flushing,traumatic tissue sampling and debridement,and wound dressing using disposable negative-pressure drainage wound protection materials,and then immediately transferred back to the experimental warehouse for 72 h negative-pressure drainage.The wound healing was observed at 24,48 and 72 h after the establishment of negative pressure drainage,and samples were taken to explore the pathological changes by HE staining.Results The firearm injury model of hind limbs in medium-sized pigs was successfully prepared,and the use of VSD system was beneficial to the healing of firearm wound in hind limbs of medium-sized pigs and reduced inflammatory reaction.In terms of safety evaluation,there was no significant difference in body mass and water intake 3 d after firearm injury in medium-sized pigs,and the model was relatively stable.Conclusion This experiment successfully establishes a firearm injury model of hind limbs with 5.8 mm wound-causing pistol,and suggests that the VSD system can effectively reduce the probability of infection of firearm injury.
Keywords：vacuum sealing drainage5.8 mm standard pistolmodelmedium-sized animal
Publication Date：2025-04-30
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)
Pages：6( 544-549 )