Analysis of clinical adverse transfusion reactions from 2016 to 2023 in a Grade-A tertiary hospital
LIU Yaxin
FU Wenda
WANG Wenting
ZHAO Na'na
LI Ying
YANG Longfei
Abstract：Objective To investigate the characteristics and clinical countermeasures of adverse transfusion reactions in patients with different blood components.Methods Clinical data of patients admitted to a Grade-A tertiary hospital from 2016 to 2023 were collected to analyze the incidence and types of adverse transfusion reactions,types of transfused blood preparations,distribution of departments where adverse transfusion reactions occurred,and treatment measures.Results A total of 96 patients in the hospital had adverse transfusion reactions from 2016 to 2023,with an incidence of 0.18‰,mainly febrile non-hemolytic transfusion reactions(0.04‰)and allergic transfusion reactions(0.14‰).The probability of adverse transfusion reactions caused by suspended red blood cells and common frozen plasma in blood preparations was relatively high.The departments with the most adverse transfusion reactions were gastroenterology(15.63％),neurosurgery(14.58％),gynecology(14.58％),oncology(12.50％)and orthopedics(12.50％).The patients with allergic reactions were treated with dexamethasone(25 cases),promethazine hydrochloride(3 cases),dexamethasone combined with promethazine hydrochloride(10 cases)and dexamethasone combined with loratadine(2 cases)after stopping blood transfusion.Patients with febrile non-hemolytic transfusion reactions were treated with dexamethasone(6 cases)and dexamethasone combined with promethazine hydrochloride(1 case)after stopping blood transfusion.Conclusion Allergic reactions and febrile non-hemolytic transfusion reactions are the main types of common adverse transfusion reactions in clinical practice.In the process of clinical blood transfusion,targeted prevention should be carried out for different types of blood preparations and clinical blood departments,and the awareness of medical personnel to identify and report adverse reactions of blood transfusion should be continuously improved to ensure the safety and effectiveness of the transfusion treatment process.
Keywords：adverse transfusion reactionallergic reactionsfebrile non-hemolytic transfusion reactionssymptomatic treatment
Publication Date：2025-04-30
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)
Pages：5( 540-543,549 )