Analysis of risk factors for perioperative complications in pediatric posterior fossa tumors

WANG Julei; HUANG Tao; ZHANG Yunze; TIAN Qilong; YANG Chen; QU Yan

doi:10.13276/j.issn.2097-1656.2025.03.014

Abstract：Objective To analyze perioperative complications following surgery for posterior fossa tumors in children and to identify associated risk factors.Methods The clinical data of children who underwent surgical resection of posterior cranial fossa tumors in Department of Neurosurgery,Tangdu Hospital,Air Force Medical University from January 2017 to August 2023 were retrospectively analyzed.The data collected included age,clinical manifestations,tumor location,preoperative secondary hydrocephalus,operation timing,surgical approach,surgical team,surgical resection degree,perioperative complications and histopathological diagnosis,and statistical analysis of the correlation between the data obtained and perioperative complications.Results A total of 144 children were included.Perioperative complications occurred in 48 patients,the complication rate was 33.3％,of which 14 cases required intervention,and 1 case died during perioperative period,with a mortality rate of 0.7％.In univariate analysis,tumor volume and location,suboccipital posterior median approach,and combined approach were statistically associated with increased complication rates(P＜0.05).There was no significant correlation between the pathological type of tumor tissue,the scope of resection and whether there was secondary hydrocephalus before operation and perioperative complications.Multivariate analysis showed that midline tumor,and tumor volume＞113 cm3(diameter＞3 cm)and surgery by a non-pediatric neurosurgeon were independent risk factors(P＜0.05).Conclusion Posterior fossa tumor resection in children has a higher risk of complications during the perioperative period.The identification of relevant risk factors is helpful to develop more accurate surgical plans,improve perioperative treatment plans,and reduce the incidence of complications.