A novel framework of network-targeted deep brain stimulation for neuropsychiatric disorders
ZHANG Jianning
ZHANG Yanyang
Abstract：The human brain can be constructed an intricate and complex network from the microscopic level of neurons and synapses,the mesoscopic level of neuronal clusters,to the macroscopic level of brain regions.Neuropsychiatric disorders such as stress disorder,chronic pain and Alzheimer's disease commonly suffer from"disconnection"of brain networks,and the treatment of such diseases is currently facing difficulties.New neuromodulation techniques such as deep brain stimulation can exert their effects by regulating brain networks.By analyzing the brain network characteristics of diseases and regulating them,it may bring hope for the treatment of neuropsychiatric disorders.Therefore,we have established a novel framework of network-targeted deep brain stimulation for neuropsychiatric disorders,including basic research on brain network characteristics and clinical research on brain network neuromodulation.In the future,further improving the theory and expanding the application of this diagnosis and treatment system will play an important role in promoting precise treatment of neuropsychiatric disorders and improving patients'quality of life.
Keywords：functional neurosurgerybrain disordersdeep brain stimulationbrain networkneuromodulationneuroscience
Publication Date：2025-03-31
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)
Pages：5( 281-285 )