Research hotspots and trend visualization analysis of TREM1 based on CiteSpace and VOS viewer
GUO Jing
QU Jingtian
ZHAO Lili
TONG Miaomiao
LI Li
Abstract：Objective To explore the development,research hotspots,and frontiers of triggering receptor expressed on myeloid cells 1(TREM1)through bibliometric analysis,so as to provide valuable information for future TREM1-related studies.Methods Literature on TREM1 research from 2005 to 2023 was searched from Web of Science.Excel 2019 was used to collect basic information about publications,research areas,etc.VOSviewer 1.6.19 was used to analyze and visualize information about countries,institutions,and authors.CiteSpace 6.2.R1 was used to analyze and visualize co-cited authors,co-cited references,keyword clustering and keyword emergence.Results A total of 1 134 articles were retrieved,including 1 735 research institutions and 503 academic journals.The countries and institutions with the most TREM1-related publications were China(327 articles)and Institut National de la Santé et de la Recherche médicale(41 articles).In particular,BOUCHON A had the highest number of co-citations(494).The analysis of co-occurrence of keywords suggested that inflammatory bowel disease,septic shock,and Alzheimer's disease were the research hotspots.Hot keywords suggested cutting-edge topics,including biomarkers,Alzheimer's disease,microglia,mechanisms,cerebrospinal fluid,oxidative stress,and pathways.Conclusions The research directions of TREM1 include inflammatory bowel disease,septic shock,Alzheimer's disease,microglia,biomarkers,oxidative stress,and different pathways.In the future,we need to deeply explore the mechanism of its action in the occurrence and development of various diseases.
Keywords：triggering receptor expressed on myeloid cells 1CiteSpaceVOSviewervisualization
Publication Date：2025-02-27
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)
Pages：7( 242-248 )