Effect of electrical acupoint stimulation on EEG power spectral density during 24 h head down bed rest in human body
LIU Zhi
LI Shuhan
LI Chengfei
PAN Yikai
SUN Kewei
ZHANG Yunfei
LI Xiaoying
WANG Yongchun
CUI Guangbin
SUN Xiqing
Abstract：Objective To observe the changes of electroencephalogram(EEG)and the effect of electrical acupoint stimulation during 24 h simulated weightlessness in head down bed rest.Methods A total of 22 volunteers were randomly divided into electroacupuncture group and control group,with 11 people in each group.The control group rested in bed in a head-low position for 24 h,while the electroacupuncture group rested in bed in a head-low position for 24 h and then stimulated bilateral Neiguan acupoints for 30 min.The changes of power spectral density(PSD)of EEG signals in resting state and mood states were analyzed and compared between the two groups before and after bed rest.Results Compared with that before bed rest,the PSD of θ and α band generally decreased in all brain regions,the PSD of right temporal lobe θ band and the PSD of right central region,right parietal lobe,and left occipital lobe α band significantly reduced(P＜0.05).The score of fatigue,depression,and anger,as well as the total score of negative mood disorder of Profile of Mood States(POMS)significantly increased(P＜0.05),while the score of energy significantly decreased(P＜0.05)after 24 h of head down bed rest.Compared with the control group,the PSD in the right frontal lobe θ band was significantly reduced in the electroacupuncture group(P＜0.05),and the depression score of POMS showed a decreasing trend after bed rest.Conclusion The simulated weightlessness effect of 24 h head down bed rest alters the activities of θ and α band of certain brain regions at rest,and can be more likely to cause negative emotions.Electroacupuncture stimulation regulates the activity of the right frontal lobe θ bands and potentially has a positive regulatory effect on the activity of α bands of various brain regions.To some extent,electroacupuncture stimulation also alleviates the generation of negative emotions caused by head down bed rest.
Keywords：electroacupuncture stimulationNeiguan acupointhead down bed restelectroencephalogram
Publication Date：2025-01-27
Online Publishing Date：2026-08-26(First online date of this platform, not the publication date of the document)