Observation on the effect of ultrasound-guided fine-needle injection of methotrexate in the treatment of tubal ectopic pregnancy
JIANG Wanting
YUAN Na
LI Lingmin
WANG Jianhong
GAO Liang
Abstract：Objective To evaluate the efficacy and safety of ultrasound-guided fine-needle injection of methotrexate(MTX)in the treatment of tubal ectopic pregnancy.Methods A total of 80 patients with tubal ectopic pregnancy were randomly as-signed to either the observation group or the control group,with 40 cases in each group.The observation group received ultrasound-guided fine-needle injection of MTX,while,the control group was treated with intramuscular injection of MTX.Se-rum β-HCG levels,gestational sac size,overall symptom improvement,overall adverse reaction rate,and treatment failure rate were compared between the two groups before and after treatment.Results Both groups showed a reduction in serum β-HCG levels and a decrease in gestational sac size after treatment compared to before treatment(P<0.05).Compared with the control group,the observation group showed a greater reduction in serum β-HCG levels and gestational sac size after treat-ment,along with a higher symptom relief rate and lower rates of adverse reactions and treatment failure,all with statistically significant differences(P<0.05).Conclusion Ultrasound-guided fine-needle injection of MTX can effectively improve the therapeutic efficacy for tubal ectopic pregnancy and reduce the incidence of adverse reactions and treatment failure,thereby providing patients with a safer and more effective treatment option.
Keywords：InterventionalradiologyFine needle aspirationUltrasound examinationTubal pregnancyMethotrexate
Publication Date：2026-01-30
Online Publishing Date：2026-03-20(First online date of this platform, not the publication date of the document)
Pages：4( 126-129 )