The relationship between shear wave elastography,contrast-enhanced ultrasound,and color Doppler flow imaging pa-rameters and the histological grade of breast cancer as well as lymph node metastasis
WANG Lijie
LU Zhaoan
LIU Hui
XU Juan
WANG Nan
XIE Qingqing
ZHANG Huimin
Abstract：Objective To investigate the relationship between shear wave elastography(SWE),contrast-enhanced ultra-sound(CEUS),and color Doppler flow imaging(CDFI)parameters and the histological grade of breast cancer as well as lymph node metastasis.Methods A total of 96 patients with breast cancer(malignant group)and 96 patients with benign breast nod-ules(benign group)were selected,and all underwent SWE,CEUS and CDFI examinations.All of them underwent SWE,CEUS and CDFI.The parameters of SWE,CEUS and CDFI in patients with different pathological characteristics in the malignant group,the benign group and the malignant group were analyzed,and the correlation between SWE,CEUS and CDFI parameters and pathological characteristics was analyzed.Results The Emin,Emean,Emax,AUC,PI,PSV and RI in the malignant group were higher than those in the benign group,and the TTP was lower than that in the benign group(all P<0.05).There were signifi-cant differences(all P<0.05)in Emin,Emean,Emax,AUC,PI,PSV,RI,and TTP among patients with different histological grades and lymph node metastasis.As the histological grade increased and lymph node metastasis occurred,Emin,Emean,Emax,AUC,PI,PSV,and RI showed an increasing trend,while,TTP showed a decreasing trend(all P<0.05).Emin,Emean,Emax,AUC,PI,PSV and RI were significantly positively correlated with histological grade and lymph node metastasis,while,TTP was significantly negatively correlated with histological grade and lymph node metastasis(all P<0.05).Conclusion The change of SWE,CEUS,CDFI parameters of breast cancer is closely related to histological grade and lymph node metastasis.
Keywords：Shear wave elastic imagingContrast-enhanced ultrasoundColor Doppler flow imagingBreast cancer
Publication Date：2026-01-30
Online Publishing Date：2026-03-20(First online date of this platform, not the publication date of the document)
Pages：5( 51-54,80 )