Advances in the application of SPECT/CT for the diagnosis of common orthopedic diseases
GU Longxuan
LI Tong
QU Lei
WANG Jiyuan
YAO Shuzhan
Abstract：With the continuous advancement of nuclear medicine imaging technology,the fusion technology of single-photon emission computed tomography(SPECT)and CT(SPECT/CT)has developed rapidly.SPECT/CT examination is a nuclear medi-cine imaging technology that integrates functional metabolic imaging with high-resolution anatomical structures.It can precisely locate and quantitatively assess lesions in a single examination,significantly improving the diagnostic accuracy and specificity of bone tumors and infectious,metabolic,and ischemic bone diseases.Future research will focus on the optimization of imaging re-construction algorithms,the reduction of scanning time,and the development of new long-half-life molecular probes.At the same time,it will promote the integration of artificial intelligence and radiomics in the image analysis of SPECT/CT examinations,with the aim of extending SPECT/CT examinations to primary screening and long-term dynamic follow-up scenarios,thereby promot-ing the transformation of orthopedic diseases from"morphological diagnosis"to"function-molecular precision diagnosis and treat-ment".
Keywords：Single-photon emission computed tomographyTomographyX-ray computedOrthopedic diseasesImaging diagnosis
Publication Date：2025-12-30
Online Publishing Date：2026-02-04(First online date of this platform, not the publication date of the document)
Pages：6( 158-162,167 )