Value of color Doppler flow imaging combined with grayscale ultrasound in the early diagnosis of benign and malig-nant breast nodules

LIU Fujuan; XU Guoxia; WANG Suping; ZHANG Xiaoyong; XU Linxia

doi:10.20258/j.cnki.1006-9011.2025.10.019

Abstract：Objective To explore the role of color Doppler flow imaging(CDFI)combined with grayscale ultrasound in the early diagnosis of benign and malignant breast nodules.Methods 28 patients admitted to our hospital with malignant breast nodules confirmed by pathological examination were classified as malignant group,and 84 patients with benign breast nodules were classified as benign group.CDFI and grayscale ultrasound were applied to diagnose benign and malignant breast nodules.Kappa test was used to analyze the consistency of different diagnostic methods of benign and malignant breast nodules and patho-logical results.ROC curve was applied to analyze the diagnostic value of CDFI combined with gray-scale ultrasound for benign and malignant breast nodules.Results The Kappa test showed that the consistency of CDFI combined with grayscale ultra-sound in diagnosing benign and malignant breast nodules(Kappa value=0.783)was higher than that of CDFI(Kappa value=0.653)and grayscale ultrasound alone(Kappa value=0.692).There were obvious differences between the benign group and the malignant group in terms of nodule boundary,morphology,enhancement,calcification,posterior echo attenuation,and blood flow signal grading(P<0.05).Compared with the benign group,the malignant group showed an obvious increase in peak systolic flow velocity and resistance index(P<0.05).ROC curve analysis showed that the AUC of CDFI combined with grayscale ultra-sound for the diagnosis of benign and malignant breast nodules was obviously higher than that of CDFI and grayscale ultrasound alone(Z was 2.360,1.915,P<0.05).Conclusion CDFI combined with gray scale ultrasound can improve the early diagnosis efficiency of benign and malignant breast nodules,and provide a new diagnostic method for clinical research.