The diagnostic value of CDUS combined with TCCS examination for the abnormal blood flow spectrum morphology in vertebral artery hypoplasia patients
WANG Yinrong
FU Xiaohong
WU Xujuan
Abstract：Objective To investigate the diagnostic value of combined color Doppler ultrasonography(CDUS)and transcra-nial color Doppler sonography(TCCS)examination in the detection of abnormal blood flow spectrum morphology in vertebral ar-tery hypoplasia(VAH)patients.Methods 437 patients with unilateral VAH who were screened by color doppler ultrasound(CDUS)combined with transcranial color-coded duplexsonography(TCCS)were selected.Those patients were divided into nor-mal group(295 cases)and abnormal group(142 cases)according to whether the VA blood flow spectrum morphology was nor-mal on the VAH side.The relevant data of patients,including gender,age,and classification of the VAH side,bilateral verte-bral artery(VA)diameters of intervertebral segment,peak systolic flow velocity(PSV),end-diastolic flow velocity(EDV)of in-tracranial segment and extracranial segment,vascular resistance index(RI)of extracranial segment,vascular pulsation index(PI)of intracranial segment,and the difference of VA diameter on both sides,were calculated.Results According to whether the VA blood flow spectrum morphology was normal on the VAH side,the gender of patients,extracranial segment(bilateral VA diameter and its difference,PSV and EDV of the VAH side,bilateral RI),intracranial segment(PSV and EDV of the VAH side)were correlated with abnormal blood flow spectrum morphology in VAH patients(P<0.01).Multivariate logistic re-gression analysis showed that the difference of bilateral VA diameter,VA diameter on the VAH side,PSV and EDV of intracra-nial and extracranial segments were independent risk factors for abnormal blood flow spectrum morphology in VAH(P<0.01).The area of extracranial EDV was the largest.In case of the bilateral VA diameter difference≥1.20 mm,or VAH side VA diameter≤2.05 mm or extracranial segment PSV≤40.85 cm/s,EDV≤12.20 cm/s,or intracranial segment PSV≤40.85 cm/s,EDV≤15.95 cm/s,the sensitivity and specificity of blood flow spectrum morphologic abnormalities were the highest of VAH.Conclusion The dif-ference of bilateral VA diameter,VA diameter on the VAH side,PSV and EDV in intracranial and extracranial segments are in-dependent risk factors for abnormal blood flow spectrum morphology in VAH.
Keywords：Vertebral artery hypoplasiaColor doppler ultrasonographyBlood flow spectrum morphology
Publication Date：2025-08-30
Online Publishing Date：2025-09-28(First online date of this platform, not the publication date of the document)
Pages：6( 28-33 )