Qualitative diagnostic value of breast lesions using DCE-MRI combined with IVIM technology
HU Xiankuo
YUAN Yushan
ZHANG Lei
MA Peiqi
ZHANG Yang
Abstract：Objective To explore the qualitative diagnostic value of benign and malignant breast lesions using dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with voxel based incoherent motion(IVIM)technology.Methods A total of 106 patients with breast lesions who were treated in the hospital were selected and examined by DCE-MRI and IVIM.The parameters of DCE-MRI,in terms of peak time(Tpeak),early signal enhancement rate(SER),maximum en-hancement rate(Epeak),and IVIM technical parameters,such as true diffusion coefficient(D),perfusion-related diffusion co-efficient(D *),perfusion fraction(f),apparent diffusion coefficient(ADC)were statistically analyzed.The value of DCE-MRI and IVIM in the diagnosis of benign and malignant breast lesions was discussed by receiver operating characteristic curve(ROC).Results According to breast biopsy or surgical pathology results,among 106 patients with breast lesions,a total of 78 cases(73.58%)were diagnosed with malignant breast lesions and 28 cases(26.42%)with benign breast lesions.The SER,Epeak,and f of patients with malignant breast lesions were significantly higher than those of patients with benign breast lesions,while,Tpeak,D,D*,and ADC were significantly lower than those of patients with benign breast lesions,and the differences were statistically significant(P<0.05).ROC curve was drawn,and the results showed that the area under the curve(AUC)val-ues for Tpeak,SER,Epeak,D,D*,f,ADC,and their combined diagnosis of benign and malignant breast lesions were 0.650,0.663,0.683,0.669,0.700,0.693,0.665,and 0.919,respectively,indicating that the combined diagnostic value was the highest.Conclusion DCE-MRI combined with IVIM technology has high diagnostic value for benign and malignant breast le-sions,which can be used as a non-invasive diagnostic method for qualitative diagnosis of breast lesions.
Keywords：Breast lesionsMagnetic resonance imagingIntravoxel incoherent motionQualitative diagnosis
Publication Date：2025-07-30
Online Publishing Date：2025-08-26(First online date of this platform, not the publication date of the document)
Pages：5( 72-76 )