A comparative study on the analgesic effects of Ultrasound-guided serratus anterior plane block and pecs Ⅱ block after modified radical mastectomy for breast cancer
YANG Xuewei
WEI Fei
LIU Yingxin
ZHANG Jun
GENG Licheng
Abstract：Objective The objective of this study was to compare the postoperative analgesic effects of ultrasound-guided ser-ratus anterior plane block(SPB)and PECS Ⅱ block in patients undergoing modified radical mastectomy.Method Sixty-four breast cancer patients with ASA grade Ⅰ to Ⅱ,aged 25 to 65 years,who underwent elective modified radical mastectomy,were randomly divided into SPB group and PECS Ⅱ block group,with 32 cases in each group.After general anesthesia,the patients in two group received a ultrasound-guided SPB or PECS Ⅱ block,with 25 mL of 0.375%ropivacaine,respectively.The primary outcome measures were visual analog scale(VAS)score at rest,and VAS score during shoulder exercise at different time points(1,2,4,8,12,24 h),the secondary outcome measures were morphine dosage 24 h after surgery and opioid-related adverse reac-tions.Results There was no significant difference in VAS score between the ultrasound-guided SPB group and PECS Ⅱ block group(P>0.05).There was no significant difference in the dosage of morphine and opioid-related adverse reactions 24 h after sur-gery(P>0.05).Conclusion Both ultrasound-guided SPB and PECS Ⅱ block can provide satisfactory analgesia for patients un-dergoing modified radical mastectomy.The analgesic effect of the two nerve block methods is similar.
Keywords：UltrasoundSerratus anterior plane blockPectoralis nerve blockModified radical mastectomy for breast can-cerBreast cancer
Publication Date：2025-06-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 66-70 )