Clinical application of low-dose CT-guided percutaneous pancreatic puncture biopsy

LIN Youdan; QIN Bin; SUN Shuwen; LIU Xisheng

doi:10.20258/j.cnki.1006-9011.2025.05.018

Abstract：Objective To explore the diagnostic efficacy,safety and radiation reduction of low-dose CT-guided percutaneous pancreatic puncture biopsy.Methods A total of 126 patients who underwent CT-guided percutaneous pancreatic biopsy in our Hospital were selected.According to the CT scanning technical parameters,the patients were divided into a conventional dose group(84 mAs)with 47 cases and a low dose group(30 mAs)with 79 cases.The diagnostic efficacy,complication rate,radia-tion dose and image quality of the two groups were compared.Results The puncture accuracy,sensitivity,specificity and com-plication rate of the low-dose group were 93.7%(74/79),93.6%(73/78),100%(1/1)and 7.6%(6/79),respectively,which were not significantly different from those of 89.4%(42/47),91.1%(41/45),100%(2/2)and 6.4%(3/47)in the conventional-dose group(P>0.05).The average dose-length product(DLP)and effective dose(ED)of the low-dose group were lower than the conventional group,with significant differences(P<0.05).The image noise value of the low-dose group was higher than that of the conventional group,and the signal-to-noise ratio(SNR)and contrast-noise ratio(CNR)were lower than those of the con-ventional group,with significant differences(P<0.05).The subjective scores of the images in both groups were≥2 points,and the consistency of the scores between observers was good(Kappa=0.762),and the image quality could meet the puncture requirements.Conclusion The use of low-dose CT-guided percutaneous pancreatic biopsy can significantly reduce the radia-tion dose,without affecting the diagnostic efficiency of puncture and increasing the incidence of complications,which deserves popularization.