Diagnostic value of STE combined with PDU in peripheral zone Lesions of the prostate and correlation analysis with Gleason score

YAN Xuelian; YANG Mingxia; YU Yanyan; MA Guifeng

doi:10.20258/j.cnki.1006-9011.2025.03.017

Abstract：Objective To analyze the diagnostic value of sound touch elastography(STE)in combination with power doppler ultrasound(PDU)in lesions of the prostate peripheral zone,and to explore its correlation with Gleason score.Methods A to-tal of 87 cases of lesions in the prostate peripheral zone were selected and categorized into a prostate cancer(PCa)group with 50 cases and a benign prostatic hyperplasia(BPH)group with 37 cases based on the results of biopsy pathology.Comparisons were conducted between the two groups in terms of Emax,Emean,and PDU.The relationship between each parameter and the Glea-son score was analyzed.ROC curves were also plotted to compare the diagnostic performance of these parameters for PCa in the peripheral zone.Results The PCa group demonstrated significantly higher values of Emax,Emean,and PDU compared to the BPH group,with statistical significance(P<0.001).Each parameter showed a positive correlation with the Gleason score(P<0.05),with Emax exhibiting the strongest correlation.The middle-and high-risk PCa groups had significantly higher Emax and Emean values than the low-risk group(P<0.001),while no statistically significant difference was observed in PDU between these two risk groups(P>0.05).The PDU of the low-risk PCa group was significantly higher than that of the BPH group(P<0.001),but there was no statistically significant difference in Emax and Emean between them(P>0.05).When Emax,Emean,and PDU were used individually for PCa detection,the areas under the curve(AUCs)were 0.815,0.801,0.794,The AUC for the combined application of these three parameters was 0.921,which was significantly higher than that of each parameter used alone(P<0.05).Conclusion STE and PDU possess diagnostic significance for PCa in the peripheral zone of the prostate,with the capability to predict the pathological grading of the cancer.Furthermore,the combined application of the two techniques demonstrates enhanced efficacy.