Study on the CT-FFR associated with coronary plaqueand perivascular adipose based on CCTA
ZHANG Ran
LI Fei
MI Yuxia
GENG Yunping
YOU Guoqing
Abstract：Objective To explore the CT-FFR associated with coronary plaque and perivascular adipose based on CCTA.Methods A retrospective study included 88patients with coronary heart disease who underwent CCTA.A total of eight features,including coronary plaque and perivascular adipose,were quantitatively obtained by dividing them into ischemic group(CT-FFR<0.8)and non-ischemic group(CT-FFR≥0.8)based on whether the CT-FFR was less than 0.8.The two sets of data were tested for normality,two independent samples t-test was used for the three sets of characteristics that conformed to normal distribution,and Wilcoxon rank sum test was used for the five sets of characteristics that conformed to non-normal distribution.Finally,corre-lation analysis was performed using Pearson's coefficient for eight features.Results The differences in five correlation indexes,i.e.,calcification score,most stenotic degree,FAI,FPI,and FV,were statistically significant(P<0.05),and all of them were negatively correlated with CT-FFR.Conclusions Coronary plaque and perivascular adipose can be used as marker factors for the progression of CT-FFR.One-stop acquisition of morphological and functional characteristics of coronary arteries based on CCTA images can provide help for early diagnosis and treatment of coronary artery disease.
Keywords：Coronary computed tomographic angiographyCoronary plaquePerivascular adiposeFractional flow reserve
Publication Date：2025-03-30
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 39-42 )