The evaluation value of chest CT pulmonary vascular parameters in patients with acute exacerbation of chronic ob-structive pulmonary disease

NIU Lei; ZHANG Nannan; LIU Guohua

doi:10.20258/j.cnki.1006-9011.2025.02.011

Abstract：Objective To explore the value of chest computed tomography(CT)pulmonary vascular parameters in evaluat-ing the severity of acute exacerbation of chronic obstructive pulmonary disease(COPD).Method A prospective study was con-ducted on 102 patients with acute exacerbation of COPD admitted to hospitals.Based on patient signs and blood gas analysis,they were divided into mild,moderate,and severe groups.All patients underwent chest CT examination within 24 hours before and after admission,and the evaluation value of chest CT pulmonary vascular parameters on the severity of COPD in patients with acute exacerbation was analyzed.Results According to the evaluation of the condition,among the 102 patients,30 cases were mild,accounting for 29.4%.There were 48 cases of moderate patients,accounting for 47.1%.There were 24 severe pa-tients,accounting for 23.5%.The percentage of pulmonary small vessel cross-sectional area to total lung area(%CSA)in the se-vere group was lower than that in the mild and moderate groups.The ratio of main pulmonary artery to ascending aorta diameter(PA/A)and the percentage of low-density attenuation area below the threshold of-950 to total lung volume(LAA%-950)were higher in the severe group than in the mild and moderate groups(P<0.05).The receiver's operating characteristic(ROC)curve was drawn,and the results showed that the area under the curve(AUC)of%CSA,PA/A,LAA%-950 alone and in combination for evaluating severe illness in patients with acute exacerbation of COPD was all greater than 0.7,indicating a certain evaluation value.The combined evaluation value was higher than that of%CSA,PA/A,LAA%-950 alone(P<0.05).Conclusion Chest CT pulmonary vascular parameters(%CSA,PA/A,LAA%-950)have certain evaluation value for the severity of COPD in pa-tients with acute exacerbation.