Assessment and analysis of brain injury in premature infants using amplitude-integrated electroencephalography com-bined with cranial ultrasound

WAN Yuan; LI Yalin; YU Yue

Abstract：Objective To explore the value of combining amplitude-integrated electroencephalogram(EEG)and cranial ul-trasound in evaluating brain injury in premature infants.Methods Clinical data of 70 preterm infants treated in our hospital were selected.According to clinical diagnosis,23 cases(32.86%)had brain injury and 47 cases(67.14%)had no brain injury.With clinical diagnosis as the gold standard,the efficacy of craniocerebral ultrasound and amplitude-integrated electroencepha-lography(EEGS)alone and combined in the evaluation of brain injury in premature infants was investigated by consistency analysis.Results The consistency between the evaluation of premature infant brain injury using cranial ultrasound and amplitude-integrated electroencephalography alone and in combination with the gold standard was 0.776,0.498,and 0.843,re-spectively.The combination of amplitude-integrated electroencephalography and cranial ultrasound had the best consistency.The accuracy and sensitivity of amplitude-integrated electroencephalography combined with cranial ultrasound in diagnosing brain injury in premature infants were generally better than those of amplitude-integrated electroencephalography and cranial ul-trasound alone(P<0.05).Conclusion The combined application of cranial ultrasound and amplitude-integrated EEG can im-prove the evaluation efficiency of brain injury in premature infants,which can provide help for clinical evaluation of the risk of brain injury in children and timely detection of early brain injury.