Comparison of cone-beam breast CT with different concentrations and injection speeds

ZHOU Chunyan; HE Haoqiang; HE Ni; WU Yaopan

Abstract：Objective To evaluate the effect of different concentration and injection flow rate of iodine contrast agent on the enhancement of CE-CBBCT lesions,in order to explore an ideal contrast agent injection scheme.Methods A total of 358 pa-tients with clinical diagnosis of breast cancer in Sun Yat-Sen University Cancer Center were collected,and all patients underwent enhanced breast CT scans.The patients were divided into 370 group and 350 group according to the concentration of contrast agent(370 mgI/ml,350 mgI/ml)used in enhanced scanning,and the enhancement effect of lesions was observed.Results The enhanced CT value of the lesion at 2 min after intravenous injection of contrast agent was greater than the enhanced CT value of the lesion at 1 min,and the difference was statistically significant(P＜0.05).At the same injection speed,there was no signifi-cant difference in the enhancement of lesions between the 370 and 350 group(P＞0.05).With the increase of injection speed,the enhancement of lesions in the 350 group and the 370 group gradually increased.There was no significant difference in the CT value of the lesion in the 370 group(P＞0.05),and the difference in the enhanced CT value of the lesion in the 350 group was sta-tistically significant(P<0.05).Conclusion The enhanced CT value of 2 min lesions is better than 1 min.At the same injection speed,the contrast-enhanced CT value of the 350 group is the same as that of the 370 group.The use of 370 contrast agent can appropriately reduce the injection speed,and the use of 350 contrast agent can appropriately speed up the injection speed.