Evaluation of left ventricular systolic synchronization in patients with type 2 diabetes mellitus by real-time three-dimensional echocardiography
MA Lan
SHAO Hongzeng
ZHAO Xinxin
LIU Yong
ZHAO Yingdong
Abstract：Objective To evaluate the left ventricular systolic synchronization in patients with type 2 diabetes mellitus(T2DM)by real-time three-dimensional echocardiography(RT-3DE).Methods A total of 60 patients with T2DM were di-vided into two groups:DM 1 group(without microangiopathy,30 cases)and DM 2 group(with microangiopathy,30 cases),other 30 healthy adults were included into control group.We compared their two-dimensional ultrasonic parameters and RT-3DE parameters,i.e.,the time to minimal systolic volume of 16-segmental standard deviation and maximum difference(Tmsv 16-SD,Tmsv 16-Dif).Cardiac cycle was standardized,Tmsv 16-SD/R-R and Tmsv 16-Dif/R-R were got,and the correlation between Tmsv 16-SD/R-R,Tmsv 16-Dif/R-R and 3D-LVEF was analyzed.Results Tmsv 16-SD,Tmsv 16-Dif,Tmsv 16-SD/R-R,Tmsv 16-Dif/R-R in DM 1 group were significantly increased than those of the control group(P＜0.05),3D-LVESV,3D-LVEF were sig-nificantly decreased and 3D-LVSV,Tmsv 16-SD,Tmsv 16-Dif,Tmsv 16-SD/R-R,Tmsv 16-Dif/R-R in DM 2 group were signifi-cantly increased than those of the control group(P<0.05).3D-LVEF was significantly decreased and 3D-SV,Tmsv 16-SD,Tmsv 16-Dif,Tmsv 16-SD/R-R,Tmsv 16-Dif/R-R were significantly increased in DM 2 group than those of the DM 1 group(P<0.05).Tmsv 16-SD/R-R and Tmsv 16-Dif/R-R were negatively correlated with 3D-LVEF(r=-0.682,-0.631 in DM 1 group,r=-0.717,-0.634 in DM 2 group,P<0.05).Conclusion T2DM can impair left ventricular diastolic and systolic function.RT-3DE can detect left ventricular systolic synchronization in patients with T2DM and evaluate the degree of left ventricular dysfunction.
Keywords：Real-time three-dimensional echocardiographyType 2 diabetes mellitusSynchronizationLeft ventricular
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 53-56,61 )