Application of contrast-enhanced ultrasound and enhanced CT in diagnosis of liver cancer and evaluation of microwave ablation

KONG Sheng; HAN Wenwen; KONG Shuhong; REN Yujie; YUE Xuewang

Abstract：Objective This study investigated the application effect of contrast-enhanced ultrasound(CEUS)and enhanced CT in diagnosis of liver cancer and response evaluation of microwave ablation.Methods A total of 79 patients with liver cancer were all subjected to CEUS and enhanced CT.With pathological examination as the gold standard,diagnostic consistency of the two methods was compared.After microwave ablation,patients were subjected to CEUS and enhanced CT to assess the efficacy,and the consistency was compared.Results There was no significant difference in diagnostic accuracy between CEUS and CT(P>0.05).No significant difference in the maximal cross-sectional area of lesions was found between CEUS and enhanced CT,and there was no significant difference in evaluation of therapeutic efficiency between the two methods(P>0.05)before and 1 and 3 months after treatment.Bland-Altman test showed that there was a strong consistency between CEUS and enhanced CT in the measured maximum cross-sectional area of lesions at 1 and 3 months after treatment.Linear regression analysis showed that maximum section cross-sectional area measured by CEUS was significantly correlated with that detected by enhanced CT.Con-clusion The results suggest that diagnostic efficiency of CEUS is similar to that of enhanced CT,and both show high sensitivity and specificity.Two methods show high consistency in evaluating the curative effect of MVA.CEUS can achieve real-time obser-vation of focal blood flow perfusion,which is more economically affordable and convenient.