The clinical value of CT high-resolution algorithm and standard algorithm image reconstruction density measurement in the differential diagnosis of subcentimeter pulmonary nodules

JIANG Xiatong; CHENG Qiongqiong; PANG Minxia

Abstract：Objective To investigate the difference between high-resolution and standard image reconstruction on sub-centimeter lung nodule CT value measurement,and its influence on differential diagnosis of benign and malignant pulmonary nodules.Methods Ninety-eight patients with subcentimeter pulmonary nodules with CT value≥0 HU(according to the defini-tion formula of CT value,the CT value of water is 0 HU)were selected by high-resolution thin-layer reconstruction images with surgical and pathological results in our hospital,and thin-layer reconstruction images with standard algorithm were also avail-able.In order to further distinguish the completely solid nodular from the small number of air-bearing nodular,CT values of water were taken as the boundary,and the reconstructed images were divided into two groups according to the standard algorithm to measure CT values≥0 HU(n=52 cases)and<0 HU(n=46 cases).The differences of CT values measured by different reconstruc-tion algorithms and the pathological benign and malignant probability changes between the two groups were compared,and the di-agnostic efficiency was analyzed.Results All the CT values of the high-resolution algorithm were higher than those of the stan-dard algorithm,and the difference was statistically significant between the two groups(P<0.01).Among all the enrolled cases with CT values≥0 HU measured by high-resolution algorithm,37%(36/98)were malignant and 63%(62/98)were benign.There were 52 cases of lesions whose CT value was still≥0 HU measured by standard algorithm,and the benign proportion in-creased to 85%(44/52).The CT value of the lesions was<0 HU in 46 cases,and the malignant rate increased to 61%(28/46).ROC curve showed that the CT value of standard algorithm was more effective than that of high resolution algorithm in differentiat-ing benign and malignant lesions.Conclusion Using standard algorithm to reconstruct image to observe and measure lesion density is higher,and the resolution algorithm is more real and accurate.