Analysis of the value of the model based on CT and clinical indicators in differentiating parotid basal cell adenoma from pleomorphic adenoma

LU Li; LIU Chengliang; ZUO Chao; YU Shujing

Abstract：Objective To investigate the value of dual-phase enhanced CT and clinical index model in differentiating parotid basal cell adenoma(BCA)and pleomorphic adenoma(PA).Methods 95 patients with BCA and PA confirmed by surgery and pathology were selected,of whom 18 patients with BCA were included in the BCA group and 77 patients with PA were included in the PA group.CT plain scan and dual-phase enhanced findings and clinical data of the two groups were compared.The differen-tial model of BCA and PA was established based on two-phase enhanced CT and clinical data.Results There was no statistical significance in plain scan CT value of BCA group compared with PA group(P>0.05),but the enhancement amplitude of arterial phase and venous phase in BCA group were significantly higher than those in PA group(P<0.05).There was no statistical signifi-cance in the course of disease,maximum tumor diameter,gender,location,location,density,shape,boundary,ipsilateral tu-mor lymph nodes,smoking history,and drinking history in BCA group(P>0.05).The rate of age≥50 and soft palpation in BCA group were significantly higher than those in PA group(P<0.05).The Hosmer-Lemeshow fit test showed that the model had a good fit(χ2=0.379,P=1.000).ROC analysis showed that the AUC for the differential diagnosis of BCA and PA in a models con-structed by combining biphasic enhanced CT and clinical indicators was 0.966,the Yoden index was 0.931,the sensitivity and specificity were 94.4%and 98.7%,the 95%CI was(0.902～1.000),and the accuracy was 97.89%.Conclusion The identifica-tion model of BCA and PA based on dual-phase enhanced CT and clinical data is effective,whcih can provide auxiliary reference for the identification of BCA and PA.