Value of GLS detected by two-dimensional speckle tracking imaging in evaluating myocardial injury in patients with septic shock

YIN Ran; LYU Nan; YU Ding

Abstract：Objective To investigate the value of left ventricular global longitudinal strain(GLS)measured by two-dimensional speckle tracking imaging(2D STI)in the evaluating of myocardial injury in patients with septic shock.Methods 117 patients with septic shock and 102 healthy volunteers were selected as the observation group and control group,respectively.The GLS,left ventricular ejection fraction(LVEF)and serum cardiac troponin I(cTnI)and N-terminal B-type brain natriuretic peptide precursor(NT-proBNP)were examined.The correlations between GLS and LVEF,cTnI,NT-proBNP in patients with septic shock were analyzed.The receiver operating characteristic(ROC)curve was drawn to analyze the evaluation value of GLS for myocardial injury.Results The absolute values of GLS and LVEF in observation group were lower than control group(P<0.05),but cTnI and NT-proBNP levels were higher than control group(P<0.05).The GLS absolute value was positively corre-lated with LVEF in patients with septic shock(P<0.05),but it was negatively correlated with serum cTnI and NT-proBNP levels(P<0.05).The absolute value of GLS[(16.26±2.69)%]of myocardial injury patients was lower than non myocardial injury pa-tients[(21.78±1.45)%](P<0.001).The best cutoff point of GLS value in the diagnosis of myocardial injury in septic shock pa-tients was-20.259,and sensitivity was 84.15%,and specificity was 80.00%,and the area under the curve was 0.815.Conclu-sion The GLS value in 2D STI technology has good diagnostic value for myocardial injury in septic shock patients.