The diagnostic value of shear wave elastography combined with BRAF V600E gene mutation in unclear nodules of thy-roid fine needle biopsy
SUN Zeliang
KOU Guangling
LUAN Yanyan
WANG Yuling
LIU Demei
WANG Chungaung
WANG Yingren
Abstract：Objective The purpose of this study is to investigate the diagnostic value of shear wave elastography(SWE)com-bined with BRAF V600E gene mutation detection for unclear nodules of thyroid fine needle biopsy.Methods 98 nodules with fine needle biopsy were atypical lesions or follicular lesions in our hospital,all of which received SWE measurement,BRAF V600E gene testing and surgical treatment.According to the surgical pathological results,the application value of SWE and BRAF V600E in the diagnosis of benign and malignant nodules was retrospectively analyzed.Results Of the 98 nodules,the pathological results showed 65 benign nodules and 33 malignant nodules.The sensitivity of SWE,BRAF V600E and the combi-nation of both was 78.9%,78.8%and 85.6%,and the specificity was 72.7%,93.8%and 86.7%,respectively(P<0.05).Con-clusion The area under the curve is largest by SWE and BRAF V600E,indicating that the combination is more effective than the two methods alone.
Keywords：Thyroid neoplasmShear-wave elastographyFine-needle thyroid punctureUltrasound
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 33-36 )