Study on the effect of high-concentration contrast agent combined with low-dose scanning regimen for CTA scanning of head and carotid artery
ZHANG Yanwei
FAN Hengquan
ZHANG Xueqian
TAO Yafei
JIU Xiaolin
NIU Cunzhao
ZHU Qingsong
ZHANG Ge
Abstract：Objective To investigate the clinical feasibility of high concentration contrast media combined with low mAs in head and neck CT angiography(CTA).Methods A total of 80 patients who needed head and neck CTA scans at the local hos-pital were enrolled in this study and assigned into two groups randomly.The patients in control group received Iodixanol(320 mgI/ml),with an injection volume of 50 ml and automatic mAs.The patoents in observation group received Iomeprol(400 mgI/ml),with an injection volume of 40ml,whereas the effective mAs was reduced by a factor 0.7.Tube voltage and other scanning parameters were consistent between the two groups.The quality of acquired images were assessed as well as the radiation dose.Results The general information was comparable between the two groups.There was no significant difference between the two groups in image noise,SNR and CNR(t=-1.14～1.43,all P>0.05).In the observation group,the CT values of enhanced artery were significantly higher(all P<0.001)and the dose indices were significantly lower(all P<0.001)compared to the control group.All images were qualified for accurate clinical diagnosis.Conclusions The combination of increased iodine concentration and 70%mAs can further reduce the radiation dose without image quality compromise during head and neck CTA examination.
Keywords：Contrast mediumTube currentAngiographyRadiation dosageTomographyX-ray computed
Publication Date：2024-08-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 22-25 )